a(n!) = Δ

a: leading coefficient n: degree of polynomial Δ: Finite Differences

Example

we have this table of values. lets find the leading coefficient from it.

xf(x)F.DS.DT.DQ.D
-2-54----
-1-846--
008-38--
166-236-
222161012-24
33614-2-12-24
412-24-38-36-24
It is fourth differences.
Also, If the differences are negative, then the leading coefficient is negative.
Why? because Factorial of the degrees are based off polynomial.

So, use the formula again a(n!) = Δ a(4!) = -24 a(24) = -24 a = -1